v2.0.0 - Snakemake 8 compatible

Breaking change: Requires Snakemake >= v8.20.1

Full Changelog: v1.0.1...v2.0.0

v1.0.1 - package and performance update

Updated package versions, switched to data.table::fread/fwrite, and restructured results for screens with more knockouts.

Full Changelog: v1.0.0...v1.0.1

v1.0.0 - stable version with complete docs

The workflow performs all steps of the Mixscape Vignette on all samples in the annotation file according to the parametrization in the config file.

• Calculation of local perturbation signatures
• Mixscape classification of perturbed cells versus cells with no detectable perturbation
• Visualization of Mixscape results
• Analysis of perturbation responses with Linear Discriminant Analysis (LDA)

Full Changelog: https://github.com/epigen/mixscape_seurat/commits/v1.0.0