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@epigen

Computational Epigenetics

Computational Epigenetics Research and Software

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  1. CellWhisperer CellWhisperer Public

    CellWhisperer bridges the gap between transcriptomics data and natural language, enabling intuitive interaction with scRNA-seq datasets

    Jupyter Notebook 35 5

  2. MrBiomics MrBiomics Public

    MrBiomics - Modules & Recipes augment Bioinformatics for Multi-Omics Analyses at Scale

    Python 31 1

  3. atacseq_pipeline atacseq_pipeline Public

    Ultimate ATAC-seq Data Processing, Quantification and Annotation Snakemake Workflow and MrBiomics Module.

    Python 44 2

  4. KPNN KPNN Public

    Knowledge-primed neural networks

    Python 34 8

  5. crop-seq crop-seq Public archive

    Data analysis scripts for Datlinger et. al, 2017 (doi:10.1038/nmeth.4177)

    Python 29 12

  6. enrichment_analysis enrichment_analysis Public

    A Snakemake workflow and MrBiomics module for performing genomic region set and gene set enrichment analyses using LOLA, GREAT, GSEApy, pycisTarget and RcisTarget.

    Python 28 1

Repositories

Showing 10 of 42 repositories
  • spilterlize_integrate Public

    A Snakemake workflow and MrBiomics module to split, filter, normalize, integrate and select highly variable features of count matrices resulting from experiments with sequencing readout (e.g., RNA-seq, ATAC-seq, ChIP-seq, Methyl-seq, miRNA-seq,...) including diagnostic visualizations.

    epigen/spilterlize_integrate’s past year of commit activity
    Python 11 MIT 1 4 0 Updated Nov 12, 2024
  • enrichment_analysis Public

    A Snakemake workflow and MrBiomics module for performing genomic region set and gene set enrichment analyses using LOLA, GREAT, GSEApy, pycisTarget and RcisTarget.

    epigen/enrichment_analysis’s past year of commit activity
    Python 28 MIT 1 2 0 Updated Nov 8, 2024
  • mixscape_seurat Public

    A Snakemake workflow and MrBiomics module for performing perturbation analyses of pooled (multimodal) CRISPR screens with sc/snRNA-seq read-out (scCRISPR-seq) powered by the R package Seurat's method Mixscape.

    epigen/mixscape_seurat’s past year of commit activity
    R 11 MIT 1 1 0 Updated Nov 6, 2024
  • dea_seurat Public

    A Snakemake workflow and MrBiomics module for performing differential expression analyses (DEA) on (multimodal) sc/snRNA-seq data powered by the R package Seurat.

    epigen/dea_seurat’s past year of commit activity
    R 13 MIT 11 3 0 Updated Nov 6, 2024
  • scrnaseq_processing_seurat Public

    A Snakemake workflow and MrBiomics module for processing and visualizing (multimodal) sc/snRNA-seq data generated with 10X Genomics Kits or in the MTX matrix file format powered by the R package Seurat.

    epigen/scrnaseq_processing_seurat’s past year of commit activity
    R 12 MIT 1 6 0 Updated Nov 6, 2024
  • atacseq_pipeline Public

    Ultimate ATAC-seq Data Processing, Quantification and Annotation Snakemake Workflow and MrBiomics Module.

    epigen/atacseq_pipeline’s past year of commit activity
    Python 44 MIT 2 4 0 Updated Nov 6, 2024
  • genome_tracks Public

    A Snakemake workflow and MrBiomics module for easy visualization of genome browser tracks of aligned BAM files (e.g., RNA-seq, ATAC-seq, scRNA-seq, ...) powered by the wrapper gtracks for the package pyGenomeTracks, and IGV-reports.

    epigen/genome_tracks’s past year of commit activity
    Python 16 MIT 0 2 0 Updated Nov 6, 2024
  • dea_limma Public

    A Snakemake workflow and MrBiomics module for performing and visualizing differential expression analyses (DEA) on NGS data powered by the R package limma.

    epigen/dea_limma’s past year of commit activity
    R 20 MIT 1 9 1 Updated Nov 6, 2024
  • unsupervised_analysis Public

    A general purpose Snakemake workflow and MrBiomics module to perform unsupervised analyses (dimensionality reduction & cluster analysis) and visualizations of high-dimensional data.

    epigen/unsupervised_analysis’s past year of commit activity
    Python 22 MIT 3 22 0 Updated Nov 6, 2024
  • cemm.slurm.sm Public

    CeMM's Snakemake SLURM cluster profile

    epigen/cemm.slurm.sm’s past year of commit activity
    Shell 11 MIT 1 0 0 Updated Nov 6, 2024

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