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    • samtools

      Public
      Tools (written in C using htslib) for manipulating next-generation sequencing data
      C
      Other
      6101.9k17623Updated Feb 26, 2026Feb 26, 2026
    • htsjdk

      Public
      A Java API for high-throughput sequencing data (HTS) formats.
      Java
      24129627443Updated Feb 25, 2026Feb 25, 2026
    • hts-specs

      Public
      Specifications of SAM/BAM and related high-throughput sequencing file formats
      TeX
      17970118535Updated Feb 24, 2026Feb 24, 2026
    • bcftools

      Public
      This is the official development repository for BCFtools. See installation instructions and other documentation here http://samtools.github.io/bcftools/howtos/i…
      C
      Other
      26584634712Updated Feb 16, 2026Feb 16, 2026
    • htslib

      Public
      C library for high-throughput sequencing data formats
      C
      Other
      46291013626Updated Feb 6, 2026Feb 6, 2026
    • htscodecs

      Public
      Custom compression for CRAM and others.
      C
      Other
      203700Updated Feb 3, 2026Feb 3, 2026
    • www.htslib.org

      Public
      The http://www.htslib.org/ web site
      HTML
      13830Updated Dec 16, 2025Dec 16, 2025
    • c-maint

      Public
      Maintenance scripts used with the htslib/samtools/bcftools repositories
      Perl
      Other
      3301Updated Dec 9, 2025Dec 9, 2025
    • htslib-crypt4gh

      Public
      HTSlib crypt4gh plug-in
      C
      Other
      2310Updated Sep 22, 2023Sep 22, 2023
    • klib

      Public
      A standalone and lightweight C library
      C
      MIT License
      585000Updated Jan 17, 2023Jan 17, 2023
    • The http://samtools.github.io/ (master) and legacy http://samtools.sourceforge.net/ (sf-pages) web sites
      CSS
      1400Updated Dec 23, 2021Dec 23, 2021
    • tabix

      Public archive
      Note: tabix and bgzip binaries are now part of the HTSlib project.
      C
      389052Updated Aug 3, 2021Aug 3, 2021
    • Plugins for use with HTSlib
      C
      Other
      8930Updated Mar 19, 2021Mar 19, 2021
    • Staging ground for the development of the next major version of HTSJDK
      Java
      BSD 3-Clause "New" or "Revised" License
      362110Updated Mar 4, 2019Mar 4, 2019
    • sapi

      Public
      Sequence Alignment Programming Interface
      C
      0700Updated Mar 9, 2012Mar 9, 2012