Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Fix typo in URL in sctransform_vignette.Rmd #8404

Open
wants to merge 1 commit into
base: develop
Choose a base branch
from
Open
Changes from all commits
Commits
File filter

Filter by extension

Filter by extension

Conversations
Failed to load comments.
Loading
Jump to
Jump to file
Failed to load files.
Loading
Diff view
Diff view
2 changes: 1 addition & 1 deletion vignettes/sctransform_vignette.Rmd
Original file line number Diff line number Diff line change
Expand Up @@ -34,7 +34,7 @@ knitr::opts_chunk$set(
Biological heterogeneity in single-cell RNA-seq data is often confounded by technical factors including sequencing depth. The number of molecules detected in each cell can vary significantly between cells, even within the same celltype.
Interpretation of scRNA-seq data requires effective pre-processing and normalization to remove this technical variability.

In [our manuscript](https://genomebiology-biomedcentral-com/articles/10.1186/s13059-021-02584-9) we introduce a modeling framework for the normalization and variance stabilization of molecular count data from scRNA-seq experiments. This procedure omits the need for heuristic steps including pseudocount addition or log-transformation and improves common downstream analytical tasks such as variable gene selection, dimensional reduction, and differential expression. We named this method `sctransform`.
In [our manuscript](https://genomebiology.biomedcentral.com/articles/10.1186/s13059-021-02584-9) we introduce a modeling framework for the normalization and variance stabilization of molecular count data from scRNA-seq experiments. This procedure omits the need for heuristic steps including pseudocount addition or log-transformation and improves common downstream analytical tasks such as variable gene selection, dimensional reduction, and differential expression. We named this method `sctransform`.

Inspired by important and rigorous work from [Lause et al](https://genomebiology.biomedcentral.com/articles/10.1186/s13059-021-02451-7), we released an [updated manuscript](https://link.springer.com/article/10.1186/s13059-021-02584-9) and updated the sctransform software to a v2 version, which is now the default in Seurat v5.

Expand Down