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PMBL_genes

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rdmorin edited this page Dec 12, 2024 · 14 revisions

title: 'PMBL genes' bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

Origins of PMBL genes

Tier 1, high-confidence PMBL genes

46 total

Gene Summary First PMBL study Other entities QC result
ACTB Tier 1 GE[@wienandGenomicAnalysesFlowsorted2019], aSHM Wienand et al [@drevalGeneticSubdivisionsFollicular2023; @lohrDiscoveryPrioritizationSomatic2012]
ARID1A Tier 1 GE[@wienandGenomicAnalysesFlowsorted2019], FE[@barisicARID1AOrchestratesSWI2024] Wienand et al [@krysiakRecurrentSomaticMutations2017; @loveGeneticLandscapeMutations2012; @rossiCodingGenomeSplenic2012; @zhangGeneticHeterogeneityDiffuse2013]
ARID5B Tier 1 GE[@gomezUltraDeepSequencingReveals2023] Gomez et al [@reddyGeneticFunctionalDrivers2017]
B2M Tier 1 GE[@reichelFlowSortingExome2015], FE[@challa-malladiCombinedGeneticInactivation2011] Reichel et al [@morinFrequentMutationHistonemodifying2011; @pararajalingamCodingNoncodingDrivers2020]
BIRC6 Tier 1 GE[@sarkozyMutationalLandscapeGray2021] Sarkozy et al [@reddyGeneticFunctionalDrivers2017]
BTG1 Tier 1 GE[@sarkozyMutationalLandscapeGray2021], FE[@almasmoumFrequentLossBTG12021], aSHM Sarkozy et al [@burkhardtClinicalRelevanceMolecular2022; @drevalGeneticSubdivisionsFollicular2023; @morinFrequentMutationHistonemodifying2011]
CD58 Tier 1 GE[@schneiderAlterationsCD58Gene2015], FE[@challa-malladiCombinedGeneticInactivation2011] Schneider et al [@morinFrequentMutationHistonemodifying2011]
CD83 Tier 1 GE[@dunsCharacterizationDLBCLPMBL2021], aSHM Duns et al [@morinMutationalStructuralAnalysis2013; @paneaWholeGenomeLandscape2019; @russler-germainMutationsAssociatedProgression2023]
CIITA Tier 1 GE[@mottokGenomicAlterationsCIITA2015], FE[@mottokGenomicAlterationsCIITA2015], aSHM Mottok et al [@morinFrequentMutationHistonemodifying2011]
CISH Tier 1 GE[@mottokIntegrativeGenomicAnalysis2019] Mottok et al
CREBBP Tier 1 GE[@dunsCharacterizationDLBCLPMBL2021], FE[@pasqualucciInactivatingMutationsAcetyltransferase2011] Duns et al [@loveGeneticLandscapeMutations2012; @parryWholeExomeSequencing2013; @pasqualucciInactivatingMutationsAcetyltransferase2011]
CSF2RB Tier 1 GE[@reichelFlowSortingExome2015] Reichel et al
DDX3X Tier 1 GE[@mottokIntegrativeGenomicAnalysis2019], FE[@gongSequentialInverseDysregulation2021] Mottok et al [@reddyGeneticFunctionalDrivers2017; @schmitzBurkittLymphomaPathogenesis2012]
DTX1 Tier 1 GE[@gomezUltraDeepSequencingReveals2023], aSHM Gomez et al [@loveGeneticLandscapeMutations2012; @rossiCodingGenomeSplenic2012; @zhangGeneticHeterogeneityDiffuse2013]
DUSP2 Tier 1 GE[@dunsCharacterizationDLBCLPMBL2021], aSHM Duns et al [@drevalGeneticSubdivisionsFollicular2023; @lohrDiscoveryPrioritizationSomatic2012]
EBF1 Tier 1 GE[@reichelFlowSortingExome2015], FE[@ramirez-komoSpontaneousLossLineage2017], aSHM Reichel et al [@bohleRoleEarlyBcell2013; @drevalGeneticSubdivisionsFollicular2023; @thomasGeneticSubgroupsInform2023]
EEF1A1 Tier 1 GE[@reichelFlowSortingExome2015] Reichel et al [@chapuyMolecularSubtypesDiffuse2018; @hubschmannMutationalMechanismsShaping2021]
EZH2 Tier 1 GE[@mottokIntegrativeGenomicAnalysis2019], FE[@sneeringerCoordinatedActivitiesWildtype2010] Mottok et al [@loveGeneticLandscapeMutations2012; @morinSomaticMutationsAltering2010]
GNA13 Tier 1 GE[@reichelFlowSortingExome2015], FE[@muppidiLossSignalingGa132014] Reichel et al [@loveGeneticLandscapeMutations2012; @morinFrequentMutationHistonemodifying2011]
HIST1H1B Tier 1 GE[@sarkozyMutationalLandscapeGray2021], aSHM Sarkozy et al [@chapuyMolecularSubtypesDiffuse2018; @krysiakRecurrentSomaticMutations2017]
HIST1H1E Tier 1 GE[@reichelFlowSortingExome2015], aSHM Reichel et al [@grandeGenomewideDiscoverySomatic2019; @krysiakRecurrentSomaticMutations2017; @lohrDiscoveryPrioritizationSomatic2012]
HLA-B Tier 1 GE[@wienandGenomicAnalysesFlowsorted2019], FE[@fangazioGeneticMechanismsHLAI2021] Wienand et al [@lohrDiscoveryPrioritizationSomatic2012]
IL4R Tier 1 GE[@viganoSomaticIL4RMutations2018], FE[@viganoSomaticIL4RMutations2018], aSHM Vigano et al [@dunsCharacterizationDLBCLPMBL2021]
IRF8 Tier 1 GE[@mottokIntegrativeGenomicAnalysis2019], FE[@qiuIRF8mutantCellLymphoma2024], aSHM Mottok et al [@morinFrequentMutationHistonemodifying2011; @paneaWholeGenomeLandscape2019]
ITPKB Tier 1 GE[@reichelFlowSortingExome2015], FE[@tiacciPervasiveMutationsJAKSTAT2018], aSHM Reichel et al [@drevalGeneticSubdivisionsFollicular2023; @schmitzGeneticsPathogenesisDiffuse2018]
JAK1 Tier 1 GE[@mottokIntegrativeGenomicAnalysis2019] Mottok et al [@reddyGeneticFunctionalDrivers2017]
KMT2C Tier 1 GE[@sarkozyMutationalLandscapeGray2021] Sarkozy et al [@zhangGeneticHeterogeneityDiffuse2013; @zhangGenomicLandscapeMantle2014; @zhouSporadicEndemicBurkitt2019]
LTB Tier 1 GE[@deschGenotypingCirculatingTumor2020], aSHM Desch et al [@chapuyMolecularSubtypesDiffuse2018; @drevalGeneticSubdivisionsFollicular2023]
MAP3K14 Tier 1 GE[@ottoGeneticLesionsTRAF32012] Otto et al [@rossiAlterationBIRC3Multiple2011]
MS4A1 Tier 1 GE[@mottokIntegrativeGenomicAnalysis2019], FE[@rushtonGeneticEvolutionaryPatterns2020], aSHM Mottok et al [@rushtonGeneticEvolutionaryPatterns2020]
NFKBIA Tier 1 GE[@wienandGenomicAnalysesFlowsorted2019], FE[@jungnickelClonalDeleteriousMutations2000] Wienand et al [@russler-germainMutationsAssociatedProgression2023; @thomasMutationalAnalysisIkappaBalpha2004]
NFKBIE Tier 1 GE[@mansouriFrequentNFKBIEDeletions2016], FE[@mansouriFunctionalLossIkBe2015] Mansouri et al [@morinGeneticLandscapesRelapsed2016; @pararajalingamCodingNoncodingDrivers2020]
PIM1 Tier 1 GE[@dunsCharacterizationDLBCLPMBL2021], FE[@kuoRolePIM1Ibrutinibresistant2016], aSHM Duns et al [@burkhardtClinicalRelevanceMolecular2022; @drevalGeneticSubdivisionsFollicular2023; @pasqualucciHypermutationMultipleProtooncogenes2001]
PIM2 Tier 1 GE[@reichelFlowSortingExome2015], aSHM Reichel et al [@reddyGeneticFunctionalDrivers2017]
PTPN1 Tier 1 GE[@gunawardanaRecurrentSomaticMutations2014] Gunawardana et al
SGK1 Tier 1 GE[@dunsCharacterizationDLBCLPMBL2021], FE[@gaoSGK1MutationsDLBCL2021], aSHM Duns et al [@morinFrequentMutationHistonemodifying2011]
SOCS1 Tier 1 GE[@wenigerMutationsTumorSuppressor2006], FE[@melznerBiallelicMutationSOCS12005], aSHM Weniger et al [@drevalGeneticSubdivisionsFollicular2023; @morinFrequentMutationHistonemodifying2011]
SPEN Tier 1 GE[@sarkozyMutationalLandscapeGray2021] Sarkozy et al [@albuquerqueEnhancingKnowledgeDiscovery2017; @rossiCodingGenomeSplenic2012]
STAT6 Tier 1 GE[@ritzRecurrentMutationsSTAT62009], FE[@mentzPARP14NovelTarget2022] Ritz et al [@yildizActivatingSTAT6Mutations2015]
TNFAIP3 Tier 1 GE[@schmitzTNFAIP3A20Tumor2009], FE[@compagnoMutationsMultipleGenes2009] Schmitz et al [@compagnoMutationsMultipleGenes2009; @drevalGeneticSubdivisionsFollicular2023; @rossiAlterationBIRC3Multiple2011]
TP53 Tier 1 GE[@tiacciPervasiveMutationsJAKSTAT2018], FE[@katoUnderstandingFunctionstructureFunctionmutation2003] Tiacci et al [@beaLandscapeSomaticMutations2013; @morinFrequentMutationHistonemodifying2011; @rossiCodingGenomeSplenic2012; @wildaInactivationARFMDM2p53Pathway2004]
TRAF3 Tier 1 GE[@ottoGeneticLesionsTRAF32012] Otto et al [@pasqualucciAnalysisCodingGenome2011; @rossiAlterationBIRC3Multiple2011]
UBE2A Tier 1 GE[@reichelFlowSortingExome2015] Reichel et al [@lohrDiscoveryPrioritizationSomatic2012]
WEE1 Tier 1 GE[@reichelFlowSortingExome2015] Reichel et al [@schmitzGeneticsPathogenesisDiffuse2018]
XPO1 Tier 1 GE[@jardinRecurrentMutationsExportin2016], FE[@miloudiXPO1E571KMutationModifies2020] Jardin et al [@mareschalWholeExomeSequencing2016]
ZFP36L1 Tier 1 GE[@reichelFlowSortingExome2015], aSHM Reichel et al [@morinFrequentMutationHistonemodifying2011; @paneaWholeGenomeLandscape2019]

Tier 2, low-confidence PMBL genes

112 total

Gene Summary First PMBL study Other entities QC result
ABCA13 Tier 2 GE[@sarkozyMutationalLandscapeGray2021] Sarkozy et al [@spinaGeneticsNodalMarginal2016]
ACTG1 Tier 2 GE[@deschGenotypingCirculatingTumor2020], aSHM Desch et al [@fanComprehensiveCharacterizationDriver2020; @hubschmannMutationalMechanismsShaping2021; @spinaGeneticsNodalMarginal2016]
AKAP6 Tier 2 GE[@tiacciPervasiveMutationsJAKSTAT2018] Tiacci et al
ARIH2 Tier 2 GE[@reichelFlowSortingExome2015] Reichel et al
AXDND1 Tier 2 GE[@gomezUltraDeepSequencingReveals2023] Gomez et al
BCL2 Tier 2 GE[@sarkozyMutationalLandscapeGray2021], aSHM Sarkozy et al [@burkhardtClinicalRelevanceMolecular2022; @morinFrequentMutationHistonemodifying2011; @tanakaFrequentIncidenceSomatic1992]
BCL7A Tier 2 GE[@reichelFlowSortingExome2015], FE[@balinas-gaviraFrequentMutationsAminoterminal2020], aSHM Reichel et al [@grandeGenomewideDiscoverySomatic2019; @krysiakRecurrentSomaticMutations2017; @morinFrequentMutationHistonemodifying2011]
BIRC3 Tier 2 GE[@dunsCharacterizationDLBCLPMBL2021], aSHM Duns et al [@arthurGenomewideDiscoverySomatic2018; @beaLandscapeSomaticMutations2013; @rossiAlterationBIRC3Multiple2011]
CCND3 Tier 2 GE[@deschGenotypingCirculatingTumor2020], FE[@schmitzBurkittLymphomaPathogenesis2012] Desch et al [@jalladesExomeSequencingIdentifies2017; @morinFrequentMutationHistonemodifying2011; @richterRecurrentMutationID32012]
CDH2 Tier 2 GE[@deschGenotypingCirculatingTumor2020] Desch et al
CDH5 Tier 2 GE[@gomezUltraDeepSequencingReveals2023] Gomez et al
CDKN2A Tier 2 GE, FE[@kannengiesserFunctionalStructuralGenetic2009] [@grandeGenomewideDiscoverySomatic2019; @morinMutationalStructuralAnalysis2013; @spinaGeneticsNodalMarginal2016]
CHD8 Tier 2 GE [@grandeGenomewideDiscoverySomatic2019]
CXCR5 Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019] Mottok et al [@schmitzGeneticsPathogenesisDiffuse2018]
DGKB Tier 2 GE[@tiacciPervasiveMutationsJAKSTAT2018] Tiacci et al
DMD Tier 2 GE[@reichelFlowSortingExome2015] Reichel et al
DNAH12 Tier 2 GE[@wienandGenomicAnalysesFlowsorted2019] Wienand et al
EGR1 Tier 2 GE[@reichelFlowSortingExome2015] Reichel et al [@krysiakRecurrentSomaticMutations2017; @rossiCodingGenomeSplenic2012]
EPHA7 Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019] Mottok et al [@zhangGeneticHeterogeneityDiffuse2013]
ETS1 Tier 2 GE, aSHM [@morinFrequentMutationHistonemodifying2011; @paneaWholeGenomeLandscape2019]
EWSR1 Tier 2 GE [@pararajalingamCodingNoncodingDrivers2020]
EZR Tier 2 GE[@deschGenotypingCirculatingTumor2020], aSHM Desch et al
FAS Tier 2 GE, FE[@wangFasFADDDeathDomain2010] [@morinFrequentMutationHistonemodifying2011; @schollMutationsRegionFAS2007; @spinaGeneticsNodalMarginal2016]
FAT1 Tier 2 GE [@spinaGeneticsNodalMarginal2016]
FAT4 Tier 2 GE [@morinMutationalStructuralAnalysis2013; @parryWholeExomeSequencing2013; @zhangGenomicLandscapeMantle2014]
FOXO1 Tier 2 GE[@dunsCharacterizationDLBCLPMBL2021], FE[@trinhAnalysisFOXO1Mutations] Duns et al [@morinFrequentMutationHistonemodifying2011; @schmitzBurkittLymphomaPathogenesis2012]
GCSAM Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019] Mottok et al
GPR126 Tier 2 GE[@wenigerMutationsTumorSuppressor2006] Weniger et al
HECW2 Tier 2 GE[@reichelFlowSortingExome2015] Reichel et al
HELLS Tier 2 GE[@reichelFlowSortingExome2015] Reichel et al
HIST1H1C Tier 2 GE, aSHM [@morinFrequentMutationHistonemodifying2011; @paneaWholeGenomeLandscape2019]
HIST1H1D Tier 2 GE, aSHM [@jalladesExomeSequencingIdentifies2017; @krysiakRecurrentSomaticMutations2017; @morinMutationalStructuralAnalysis2013]
HIST1H2BC Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019], aSHM Mottok et al [@krysiakRecurrentSomaticMutations2017; @lohrDiscoveryPrioritizationSomatic2012]
HIST1H3B Tier 2 GE[@reichelFlowSortingExome2015], aSHM Reichel et al [@lohrDiscoveryPrioritizationSomatic2012]
HIST1H4C Tier 2 GE[@reichelFlowSortingExome2015] Reichel et al
HIST1H4E Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019] Mottok et al
HIST1H4J Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019] Mottok et al [@paneaWholeGenomeLandscape2019]
HLA-A Tier 2 GE[@deschGenotypingCirculatingTumor2020], FE[@fangazioGeneticMechanismsHLAI2021] Desch et al [@lohrDiscoveryPrioritizationSomatic2012]
HLA-C Tier 2 GE[@gomezUltraDeepSequencingReveals2023], FE[@fangazioGeneticMechanismsHLAI2021] Gomez et al [@chapuyMolecularSubtypesDiffuse2018]
HRNR Tier 2 GE[@dunsCharacterizationDLBCLPMBL2021] Duns et al
IGLL5 Tier 2 GE[@deschGenotypingCirculatingTumor2020], aSHM Desch et al [@chapuyMolecularSubtypesDiffuse2018; @paneaWholeGenomeLandscape2019; @russler-germainMutationsAssociatedProgression2023]
IKBKB Tier 2 GE[@wienandGenomicAnalysesFlowsorted2019] Wienand et al [@reddyGeneticFunctionalDrivers2017; @rossiAlterationBIRC3Multiple2011]
IL13RA1 Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019] Mottok et al
IL1RAPL2 Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019] Mottok et al
IRF2BP2 Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019] Mottok et al
IRF4 Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019], aSHM Mottok et al [@drevalGeneticSubdivisionsFollicular2023; @morinFrequentMutationHistonemodifying2011]
ITGB2 Tier 2 GE
ITPR3 Tier 2 GE[@tiacciPervasiveMutationsJAKSTAT2018] Tiacci et al [@loveGeneticLandscapeMutations2012]
JUNB Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019] Mottok et al [@lohrDiscoveryPrioritizationSomatic2012]
KLF2 Tier 2 GE[@deschGenotypingCirculatingTumor2020], aSHM Desch et al [@drevalGeneticSubdivisionsFollicular2023; @jalladesExomeSequencingIdentifies2017; @pasqualucciAnalysisCodingGenome2011]
KMT2D Tier 2 GE[@deschGenotypingCirculatingTumor2020], FE[@zhangDisruptionKMT2DPerturbs2015] Desch et al [@beaLandscapeSomaticMutations2013; @grandeGenomewideDiscoverySomatic2019; @morinFrequentMutationHistonemodifying2011; @rossiCodingGenomeSplenic2012]
LIMD2 Tier 2 GE[@gomezUltraDeepSequencingReveals2023] Gomez et al
LPHN3 Tier 2 GE[@dunsCharacterizationDLBCLPMBL2021] Duns et al
LRRN3 Tier 2 GE[@sarkozyMutationalLandscapeGray2021] Sarkozy et al [@zhangGeneticHeterogeneityDiffuse2013]
MAGEC2 Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019] Mottok et al
MCL1 Tier 2 GE[@dunsCharacterizationDLBCLPMBL2021] Duns et al [@paneaWholeGenomeLandscape2019; @reddyGeneticFunctionalDrivers2017]
MFHAS1 Tier 2 GE[@sarkozyMutationalLandscapeGray2021] Sarkozy et al
MPDZ Tier 2 GE[@reichelFlowSortingExome2015] Reichel et al [@morinMutationalStructuralAnalysis2013]
MYB Tier 2 GE[@deschGenotypingCirculatingTumor2020] Desch et al [@reddyGeneticFunctionalDrivers2017]
MYC Tier 2 GE[@dunsCharacterizationDLBCLPMBL2021], FE[@freieGermlinePointMutation2024], aSHM Duns et al [@jalladesExomeSequencingIdentifies2017; @johnstonCmycHypermutationBurkitt1992; @pasqualucciHypermutationMultipleProtooncogenes2001]
NCOR2 Tier 2 GE[@sarkozyMutationalLandscapeGray2021] Sarkozy et al [@schmitzBurkittLymphomaPathogenesis2012; @spinaGeneticsNodalMarginal2016]
NEK1 Tier 2 GE[@reichelFlowSortingExome2015] Reichel et al
NFKB2 Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019] Mottok et al [@reddyGeneticFunctionalDrivers2017]
NSD2 Tier 2 GE [@beaLandscapeSomaticMutations2013; @zhangGeneticHeterogeneityDiffuse2013]
NUP214 Tier 2 GE[@tiacciPervasiveMutationsJAKSTAT2018] Tiacci et al
OR13C2 Tier 2 GE[@gomezUltraDeepSequencingReveals2023] Gomez et al
OSBPL10 Tier 2 GE, aSHM [@zhangGeneticHeterogeneityDiffuse2013]
P2RY8 Tier 2 GE, FE[@muppidiLossSignalingGa132014] [@drevalGeneticSubdivisionsFollicular2023; @lohrDiscoveryPrioritizationSomatic2012; @muppidiLossSignalingGa132014]
PCBP1 Tier 2 GE [@schmitzBurkittLymphomaPathogenesis2012]
PCDH7 Tier 2 GE[@gomezUltraDeepSequencingReveals2023] Gomez et al [@zhangGeneticHeterogeneityDiffuse2013]
PCLO Tier 2 GE [@lohrDiscoveryPrioritizationSomatic2012]
PHIP Tier 2 GE
PRKDC Tier 2 GE [@hubschmannMutationalMechanismsShaping2021; @schmitzGeneticsPathogenesisDiffuse2018]
PRUNE2 Tier 2 GE[@tiacciPervasiveMutationsJAKSTAT2018] Tiacci et al
PTPRD Tier 2 GE [@drevalGeneticSubdivisionsFollicular2023; @spinaGeneticsNodalMarginal2016]
RANBP2 Tier 2 GE[@reichelFlowSortingExome2015] Reichel et al
RBM38 Tier 2 GE[@wienandGenomicAnalysesFlowsorted2019] Wienand et al
RDH12 Tier 2 GE[@gomezUltraDeepSequencingReveals2023] Gomez et al
RELN Tier 2 GE[@sarkozyMutationalLandscapeGray2021] Sarkozy et al [@zhangGeneticHeterogeneityDiffuse2013]
RFTN1 Tier 2 GE[@dunsCharacterizationDLBCLPMBL2021], aSHM Duns et al [@arthurGenomewideDiscoverySomatic2018]
RGS1 Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019] Mottok et al [@zhangGeneticHeterogeneityDiffuse2013]
RHOA Tier 2 GE, FE[@ohayreInactivatingMutationsGNA132016] [@richterRecurrentMutationID32012; @zhangGeneticHeterogeneityDiffuse2013]
S1PR2 Tier 2 GE, FE[@muppidiLossSignalingGa132014], aSHM [@drevalGeneticSubdivisionsFollicular2023; @morinFrequentMutationHistonemodifying2011; @muppidiLossSignalingGa132014]
SCN9A Tier 2 GE[@gomezUltraDeepSequencingReveals2023] Gomez et al
SENP7 Tier 2 GE[@reichelFlowSortingExome2015] Reichel et al
SETD5 Tier 2 GE[@tiacciPervasiveMutationsJAKSTAT2018] Tiacci et al [@reddyGeneticFunctionalDrivers2017]
SETDB1 Tier 2 GE[@reichelFlowSortingExome2015] Reichel et al
SIAH2 Tier 2 GE[@reichelFlowSortingExome2015] Reichel et al [@hubschmannMutationalMechanismsShaping2021]
SIN3A Tier 2 GE [@chapuyMolecularSubtypesDiffuse2018; @grandeGenomewideDiscoverySomatic2019; @rossiCodingGenomeSplenic2012]
SMAD3 Tier 2 GE
SMARCA2 Tier 2 GE
SMARCA4 Tier 2 GE, FE[@fernandoFunctionalCharacterizationSMARCA42020] [@krysiakRecurrentSomaticMutations2017; @nadeuGenomicEpigenomicInsights2020; @reddyGeneticFunctionalDrivers2017; @richterRecurrentMutationID32012]
STAT3 Tier 2 GE, FE[@huNovelMissenseM206K2013] [@morinFrequentMutationHistonemodifying2011]
STAT5B Tier 2 GE[@tiacciPervasiveMutationsJAKSTAT2018] Tiacci et al [@reddyGeneticFunctionalDrivers2017]
STRAP Tier 2 GE[@gomezUltraDeepSequencingReveals2023] Gomez et al
TAP1 Tier 2 GE [@schmitzGeneticsPathogenesisDiffuse2018]
TBC1D15 Tier 2 GE[@reichelFlowSortingExome2015] Reichel et al
TBL1XR1 Tier 2 GE, FE[@venturuttiTBL1XR1MutationsDrive2020] [@drevalGeneticSubdivisionsFollicular2023; @lohrDiscoveryPrioritizationSomatic2012; @rossiCodingGenomeSplenic2012]
TCF3 Tier 2 GE [@schmitzBurkittLymphomaPathogenesis2012]
TET3 Tier 2 GE
TICRR Tier 2 GE[@reichelFlowSortingExome2015] Reichel et al
TMSB4X Tier 2 GE, aSHM [@drevalGeneticSubdivisionsFollicular2023; @reddyGeneticFunctionalDrivers2017]
TNFRSF1B Tier 2 GE
TNIP1 Tier 2 GE[@tiacciPervasiveMutationsJAKSTAT2018] Tiacci et al
TRIP11 Tier 2 GE[@reichelFlowSortingExome2015] Reichel et al [@zhangGeneticHeterogeneityDiffuse2013]
UBR5 Tier 2 GE [@albuquerqueEnhancingKnowledgeDiscovery2017; @pararajalingamCodingNoncodingDrivers2020]
UNC5C Tier 2 GE [@lohrDiscoveryPrioritizationSomatic2012]
VMP1 Tier 2 GE[@mottokIntegrativeGenomicAnalysis2019] Mottok et al
VPS13B Tier 2 GE
WDR87 Tier 2 GE[@dunsCharacterizationDLBCLPMBL2021] Duns et al
ZCCHC11 Tier 2 GE[@tiacciPervasiveMutationsJAKSTAT2018] Tiacci et al
ZNF217 Tier 2 GE[@reichelFlowSortingExome2015] Reichel et al [@hubschmannMutationalMechanismsShaping2021]

Tier 3, retired PMBL genes

0 total

Gene Summary First PMBL study Other entities QC result

References

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