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rdmorin edited this page Jan 11, 2025 · 37 revisions

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @sarkozyMutationalLandscapeGray2021, @reddyGeneticFunctionalDrivers2017, @arthurGenomewideDiscoverySomatic2018,

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Overview

BIRC6, as a negative regulator of non-canonical NF-κB signaling, is implicated in lymphomagenesis. Mutations in the BIRC6 have been found in DLBCL and grey zone lymphoma (GZL).[@sarkozyMutationalLandscapeGray2021],[@reddyGeneticFunctionalDrivers2017]

Relevance tier by entity

include:tables/table1_BIRC6.md

Mutation incidence in large patient cohorts (GAMBL reanalysis)

DLBCL

include:tables/DLBCL_BIRC6.md

FL

include:tables/FL_BIRC6.md

Mutation pattern and selective pressure estimates

include:tables/dnds_BIRC6.md

BIRC6 Hotspots

Chromosome Coordinate (hg19) ref>alt HGVSp
chr2 32740138 T>A C3550*

include:tables/browser_BIRC6.md

Expression

include:tables/mermaid_BIRC6.md

References

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