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Identifying enterococci resistance drivers with machine learning

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EnterococciAMR

Identification of key drivers of antimicrobial resistance in Enterococcus using machine learning feature ranking (submitted to Canadian Journal of Microbiology)

Files include:

  • rast_pangenome_ml_feature.ipynb
    • machine learning and feature selection (Block HSIC Lasso & model-dependent feature importance ranking) analysis with pangenome annotated via RASTtk
    • the other pangenome features follow the same script, except the pangenome binary matrix that was resolved via respective annotation software (e.g., Prokka or Bakta)
  • plasmid_cluster_ML.ipynb
    • machine learning with predicted plasmid clusters (from MOB-suite software) encoded as presence and absence binary matrices

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Identifying enterococci resistance drivers with machine learning

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