Detects hotspot regions for somatic mutations in 3D protein structures
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Updated
Mar 12, 2024 - Python
Detects hotspot regions for somatic mutations in 3D protein structures
A tool for predicting the effects of missense mutations on protein stability changes upon missense mutation using protein sequence only. PROST uses colab AlhpaFold2 for the prediction of pdb struture from FASTA sequence.
A tool for predicting the effects of missense mutations on protein stability changes upon missense mutation using protein sequence only.
This program converts PDB to FASTA sequence and maps pdb's mutation position to fasta's position.
Deep learning framework to predict functional effects of missense variants in human
Sequence modification of proteins on atomistic level
Optimal AlphaMissense threshold based on VKGL variant classifications
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