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While processing a normalized VCF I want to see if the reference base was replaced
I think if norm changes the variant via replacing reference base it should write out the --old-rec-tag - this seems to fit with the help "Annotate modified records with INFO/STR indicating the original variant"
Example, running --check-ref=s --old-rec-tag=BCFTOOLS_OLD_VARIANT
NC_000004.12 51382327 14565929 N <DEL> . . SVLEN=-2000;SVTYPE=DEL;END=51384327
NC_000004.12 89258449 14565930 N <DUP> . . SVLEN=20474;SVTYPE=DUP;END=89278923
Output:
NC_000004.12 51382326 14565929 a <DEL> . . SVLEN=-2000;SVTYPE=DEL;END=51384326;BCFTOOLS_OLD_VARIANT=NC_000004.12|51382327|c|<DEL>
NC_000004.12 89258449 14565930 t <DUP> . . SVLEN=20474;SVTYPE=DUP;END=89278923
problems:
1st record should be NC_000004.12|51382327|N|<DEL> showing old record but is NC_000004.12|51382327|c|<DEL> (POST ref replace)
2nd record should have INFO field record was modified
The text was updated successfully, but these errors were encountered:
Thanks for all your hard work making a great tool!
While processing a normalized VCF I want to see if the reference base was replaced
I think if norm changes the variant via replacing reference base it should write out the
--old-rec-tag
- this seems to fit with the help "Annotate modified records with INFO/STR indicating the original variant"Example, running
--check-ref=s --old-rec-tag=BCFTOOLS_OLD_VARIANT
Output:
problems:
1st record should be
NC_000004.12|51382327|N|<DEL>
showing old record but isNC_000004.12|51382327|c|<DEL>
(POST ref replace)2nd record should have INFO field record was modified
The text was updated successfully, but these errors were encountered: