Release 2.2 optimized for big searches

Memory requirements greatly reduced for big searches. See https://drive5.com/reseek/resources.html. Note that the -dbsize option is now required to get accurate E-values.

Release 2.1

Updated mega files for compatibility with Muscle 5.3. For making multiple structure alignments, use Reseek v2.1 + Muscle v5.3.

Release 2.0.2

Improved speed & memory use (this build used for minor revision of paper).

Release 2.0.1

Minor update adding AQ support. AQ is an alignment quality metric similar to TM score with better sensitivity to homologs than TM.

Release 2.0

Updated E-value calculation with substantially improved sensitivity.

Version 1.2

Supports generating .mega files and distance matrices for Muscle-3D multiple structure alignment.

Release 1.1, first production release

Consolidates feature updates and fixes from earlier betas.

Beta release v1.3

Bugs fixes and improved parameters obtained after training fixes.

Beta release v1.2

Approx. 2x speed-up using AVX striped alignment filter for fast & sensitive modes,

Prototype release 1.1 for beta testing.

Early beta release, caveat emptor. Feedback encouraged and welcomed.