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Update index.html
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Replace "sequencing data" by "High coverage sequencing data" in webpage
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odelaneau authored Dec 14, 2018
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Expand Up @@ -44,7 +44,7 @@ <h2><b>S</b>egmented <b>HAP</b>lotype <b>E</b>stimation and <b>I</b>mputation <b
<div class="container">
<h1>Introduction</h1>
<div class="separator"></div>
<p>SHAPEIT4 is a fast and accurate method for <a href="https://en.wikipedia.org/wiki/Haplotype_estimation">estimation of haplotypes</a> (aka phasing) for SNP array and sequencing data. The version 4 is a refactored and improved version of the SHAPEIT algorithm with multiple key additional features:</p>
<p>SHAPEIT4 is a fast and accurate method for <a href="https://en.wikipedia.org/wiki/Haplotype_estimation">estimation of haplotypes</a> (aka phasing) for SNP array and high coverage sequencing data. The version 4 is a refactored and improved version of the SHAPEIT algorithm with multiple key additional features:</p>
<ul>
<li>It includes a Positional Burrow Wheeler Transform (PBWT) based approach to quickly select a small set of informative conditioning haplotypes to be used when updating the phase of an individual.</li>
<li>We have changed that way in which phase information in sequencing reads is input into the model. We now recommend the use of the WhatsHap tool as a pre-processing step to extract phase information from a bam file.</li>
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