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Hello @nictru,
there is a decoupler nf-core module for bulk analysis (https://nf-co.re/modules/decoupler_decoupler by @Nic-Nic and @vicpaton ) which could probably be a good starting point for this new feature. It handles multiple samples given in a matrix, so if you provide the single cell data as a matrix then it can return the enrichment scores per cells. Reach out to us if we can help,
best
Attila
https://decoupler-py.readthedocs.io/en/latest/index.html
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