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npm (node package manager) is the dependency/package manager you get out of the box when you install Node.js. It provides a way for developers to install packages both globally and locally.
Sometimes you might want to take a look at a specific package and try out some commands. But you cannot do that without installing the dependencies in your local node_modules folder. Since npm version 5.2.0 npx is pre-bundled with npm.
npx make it easy to install and manage dependencies hosted in the npm registry. You can use npx to run any GitHub gists and repositories.