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Nitrilase project - Copyright: Sarah L. Schwartz, PhD.

An ancient microbial origin for cyanide metabolism

Description: A project containing python code using ete3, seaborn, and arviz for analysis of molecular clock data for Class I nitrilases. Usage notes: Jupyter notebook (.ipynb), data files (.pkl, .chronogram, .labels from phylobayes - .datedist excluded), figure files (.png,.svg), text files (.csv), tree files.

Nitrilase molecular clock node age analysis

Caption: Molecular clock analyses including all calibrations predict a Class 1 nitrilase ancestor age between 1.88 and 1.02 Ga (Fig. 3, Table 1). The estimated range and mean age for the Class 1 ancestor varies by clock model: LN predicts the oldest age range (1.88-1.45 Ga) and mean (1.63 Ga), CIR predicts the youngest age range (1.02-1.25 Ga) and mean (1.13 Ga), and UGAM offers intermediate estimates for age range (1.57-1.18 Ga) and mean (1.32 Ga) of the Class 1 LCA.

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Nitrilase molecular clock node age analysis

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