Selective BCL-XL Antagonists Eliminate Infected Cells from a Primary-Cell Model of HIV Latency but Not from Ex Vivo Reservoirs
Ren Y, Huang SH, Macedo AB, Ward AR, Alberto WDC, Klevorn T, Leyre L, Copertino DC, Mota TM, Chan D, Truong R, Rohwetter T, Zumbo P, Dündar F, Betel D, Kovacs C, Benko E, Bosque A, Jones RB. Selective BCL-XL Antagonists Eliminate Infected Cells from a Primary-Cell Model of HIV Latency but Not from Ex Vivo Reservoirs. J Virol. 2021 Jul 12;95(15):e0242520. doi: 10.1128/JVI.02425-20. Epub 2021 Jul 12. PMID: 33980597; PMCID: PMC8274617.
Read counts and scripts for the bulk RNA-seq analysis for Ren et al. (2021) where the transcriptomes of CD4 T cells with and without HIV infection were compared.
The makefile
in the preprocessing
directory contains all details of the alignment, QC, and read count procedure.
The code_for_figure
directory contains the read counts and metadata that are needed to run the code in the .Rmd
document to generate the figures of the publication that were based on the bulk RNA-seq data set.
For further questions, please contact abc(at)med.cornell.edu.