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🦉 OwlSci — AI Co-Scientist That Never Sleeps

Describe your hypothesis. OwlSci runs your research while you sleep.

Inspired by Polsia — the AI that runs your company 24/7. OwlSci is the same idea for science: an autonomous AI agent that plans experiments, monitors literature, analyzes data, and drafts papers — all while you're asleep.

You: "Carbon dots with nitrogen doping kill cancer cells via ROS. 
      What's the optimal synthesis condition?"

OwlSci (runs nightly):
  Night 1 → Lit review: 47 papers on N-doped CD cytotoxicity
  Night 2 → Hypothesis ranking: 3 testable predictions
  Night 3 → Protocol: hydrothermal synthesis matrix (temp × time × precursor)
  Night 4 → Draft paper outline: Intro + Methods ready
  ...
  Day 30 → You wake up to a near-complete manuscript.

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What OwlSci Is

	Tools	OwlSci
Mode	You invoke	Autonomous, always running
Scope	Single task	Full research project
Time	Sync (you wait)	Async (you wake up to results)
Example	"Summarize this paper"	"Run my entire carbon dot project"

OwlSci is not a chatbot. It's a co-scientist with a key to your lab's digital infrastructure.

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Core Loop

┌─────────────────────────────────────────────┐
│              OWLSCI NIGHT CYCLE              │
│                                              │
│  🌙 You sleep                                │
│       ↓                                      │
│  📚 Literature Monitor — new papers found?   │
│       ↓                                      │
│  🧠 Hypothesis Engine — any testable ideas?  │
│       ↓                                      │
│  🧪 Experiment Planner — what to run today?  │
│       ↓                                      │
│  📊 Data Analyzer — results from yesterday?  │
│       ↓                                      │
│  ✍️  Paper Drafter — enough for a section?   │
│       ↓                                      │
│  ☀️ You wake up → Morning Briefing           │
└─────────────────────────────────────────────┘

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MVP — Phase 1

A Hermes Agent cron job that runs the OwlSci loop nightly.

Module	Function
NightWatch	Cron scheduler — fires the loop at 2 AM
LitOwl	Scan arXiv/bioRxiv for new papers matching your project
ThinkOwl	Generate hypotheses from accumulated knowledge
PlanOwl	Design next experiments
WriteOwl	Draft paper sections
MorningBrief	"Good morning. Here's what happened while you slept."

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Quick Start

git clone https://github.com/SpencerRaw/owlsci.git
cd owlsci
pip install -r requirements.txt

# Start the night cycle
python -m owlsci run --project "carbon dots for cancer therapy"

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Comparison

	Polsia	OwlSci
Domain	Startups / business	Scientific research
What it runs	Company (code, marketing, sales)	Research project (lit, exps, papers)
Goal	Revenue	Publications / discoveries
Founder	Simon Pound (solo, $1M ARR)	Open source

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Inspiration

• Polsia — AI that runs your company while you sleep
• Google AI Co-Scientist — multi-agent hypothesis generation
• Academic GStack — 18 agent roles for research

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License

MIT