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Bioinformatics
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@BilgiAILAB

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SinaBerkGolech/README.md

πŸ‘‹ Hi there, I'm Sina Berk Golech

Typing SVG

πŸ”¬ About Me

I am a Bioinformatics Researcher specializing in Metagenomics and Metabolomics analysis. My research focuses on developing and applying computational methods to understand complex biological systems through the analysis of microbial communities and metabolic pathways. I am particularly interested in genome scaffolding, biosynthetic gene cluster analysis, and multi-omics data integration.

🎯 Current Research Focus

  • πŸ”¬ Metagenomics: Microbial community analysis and taxonomic profiling
  • 🧬 Genome Scaffolding: Development and application of tools like Medusa, Multi-CSAR, and Ragout
  • πŸ“Š Metabolomics: Metabolite identification and pathway analysis
  • βš™οΈ Workflow Development: Snakemake and Nextflow pipeline optimization
  • πŸ€– Machine Learning: Application of ML methods in bioinformatics

πŸ› οΈ Technical Expertise

Programming Languages & Tools

Python R Bash JavaScript

Bioinformatics & Workflow Tools

Snakemake Nextflow Bioconductor QIIME2

Data Analysis & Visualization

Jupyter Pandas Matplotlib Seaborn

Cloud & Computing

Docker Git Linux

πŸ“Š GitHub Statistics

GitHub Stats GitHub Streak
Top Languages

πŸ”¬ Research Projects

🧬 Genome Scaffolding & Assembly

πŸ”— IAMPGutMB
Genome assembly and scaffolding analysis of gut microbiome data
View Project
🧬 Scaffolding Tools
Medusa, Multi-CSAR, Ragout implementation and optimization
In Development

πŸ“Š Metabolomics & Bioinformatics

πŸ§ͺ Metabolomics Seminar
Reproducibility case studies in metabolomics bioinformatics
View Project Stars
πŸ”¬ Biosynthetic Gene Clusters
Analysis of specialized metabolite biosynthetic diversity
Research Area

πŸ€– Machine Learning & Computer Vision

πŸ–ΌοΈ Turkish Image Captioning
Multimodal AI for Turkish language image description
View Project
🧠 ML in Bioinformatics
Machine learning applications in omics data analysis
Research Area

🌐 Personal Website & Portfolio

πŸ“„ Academic Portfolio
Personal website showcasing research, publications, and professional experience
View Project Live Website

πŸ“š Research Interests

Metagenomics

  • Microbial community analysis and taxonomic profiling
  • 16S rRNA and shotgun metagenomics data processing
  • Functional metagenomics and pathway analysis
  • Multi-omics data integration

Genome Assembly & Scaffolding

  • Medusa: Multi-reference genome scaffolding
  • Multi-CSAR: Comparative scaffolding with rearrangements
  • Ragout: Reference-assisted genome assembly
  • De novo assembly optimization and quality assessment

Metabolomics

  • Metabolite identification and quantification
  • Pathway analysis and enrichment studies
  • Integration with genomic and transcriptomic data
  • Statistical analysis of metabolic profiles

Workflow Development

  • Snakemake: Reproducible bioinformatics workflows
  • Nextflow: Scalable pipeline development
  • Containerization with Docker
  • High-performance computing optimization

🀝 Research Collaboration

I am actively seeking collaborations in:

  • Genome scaffolding algorithm development
  • Multi-omics data integration
  • Microbial community analysis
  • Bioinformatics tool development
  • Reproducible research workflows

πŸ’¬ Areas of Expertise

  • Metagenomics data analysis workflows
  • Metabolomics data processing and interpretation
  • Bioinformatics pipeline development
  • Statistical analysis of omics data
  • R and Python for bioinformatics
  • Snakemake and Nextflow workflow optimization

πŸ“« Contact Information

πŸ“ˆ Research Metrics

GitHub Trophies
Profile Views

"Advancing bioinformatics through reproducible research and innovative computational methods" πŸ§¬πŸ”¬

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  1. Metabolomics_Seminar_Topic_10 Metabolomics_Seminar_Topic_10 Public

    Case studies of reproducibility in bioinformatics: Metabolomics

    Jupyter Notebook 1

  2. IAMPGutMB IAMPGutMB Public

    Identification of antimicrobial peptides from human gut microbiome and investigation of their therapeutic potential in gastrointestinal disorders using deep learning

    1

  3. BilgiAILAB/TurkishImageCaptioning BilgiAILAB/TurkishImageCaptioning Public

    BilgiAILAB/TurkishImageCaptioning

    1