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HRA/ASCT+B ETL needs mapping of cell type to proteins #64

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AlanSimmons opened this issue Jun 27, 2023 · 1 comment
Open

HRA/ASCT+B ETL needs mapping of cell type to proteins #64

AlanSimmons opened this issue Jun 27, 2023 · 1 comment
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@AlanSimmons
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Statement of issue

The ASCT+B associates cell type with two types of biomarkers--genes and proteins. However, the HRA ETL that extracts ASCT+B information from the CCF.OWL currently only returns associations between cell types and genes.

Proposed solution

Enhance the HRA ETL to obtain cell type - protein associations.

Dependencies

  • I'm not sure whether the CCF.OWL actually has the cell type-protein associations. They are available in the ASCT+B itself, though.
  • This will likely require an enhancement to the HRA ETL, a custom python/SPARQL application.
@bherr2
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bherr2 commented Jun 27, 2023

CC'ing @johardi . We can discuss at tomorrow's meeting. What do you think about the possibility of adding the rest of the Bx (gene, protein, metabolite, etc) to the CCF.OWL (and eventually HRA v2.0)?

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