The Iridium database by OpenEye Scientific Software contains high-quality, verified protein structures that are recommended for lead optimization, docking, and virtual screening.
Warren, G.L., Do, T.D., Kelley, B.P., Nicholls, A. and Warren, S.D. (2012), “Essential considerations for using protein–ligand structures in drug discovery”, Drug Discovery Today, Vol. 17 No. 23-24, pp. 1270–1281.
The database is freely available at http://www.eyesopen.com/iridium
** A more detailed table can be found here **
<img src='./images/iridium_detailed.png', alt=''>
1A28, 1AI5, 1AZM, 1B9V, 1BR6, 1C1B, 1CTR, 1CVU, 1CX2, 1D3H, 1DD7, 1DDS, 1EOC, 1EXA, 1EZQ, 1F0S, 1F0T, 1F0U, 1FCX, 1FCZ, 1FH8, 1FH9, 1FHD, 1FJS, 1FL3, 1FM6, 1FM9, 1FQ5, 1FRP, 1FVT, 1G9V, 1GM8, 1GWX, 1H1P, 1H1S, 1HDY, 1HGG, 1HGH, 1HGI, 1HGJ, 1HNN, 1HP0, 1HQ2, 1HVY, 1HWI, 1HWW, 1IVB, 1IVD, 1IVE, 1IVF, 1IY7, 1JD0, 1JLA, 1K1J, 1K3U, 1KE5, 1L2S, 1L7F, 1LPZ, 1LQD, 1LRH, 1M2Z, 1MBI, 1ML1, 1MMV, 1MQ6, 1MTS, 1MZC, 1N1M, 1N2J, 1N2V, 1NAV, 1OF1, 1OF6, 1OQ5, 1OWE, 1OYT, 1P2Y, 1P62, 1PBD, 1PMN, 1PSO, 1Q1G, 1Q41, 1QHI, 1R58, 1R9O, 1ROB, 1S19, 1SQ5, 1TOW, 1TT1, 1U4D, 1UKZ, 1ULB, 1UML, 1UNL, 1UOU, 1V0P, 1W1P, 1W2G, 1X8X, 1XM6, 1XOQ, 1YDR, 1YDS, 1YDT, 1YQY, 1YV3, 1YVF, 1YWR, 2ACK, 2BR1, 2CTC, 2MCP, 2PCP, 2TMN, 3PTB, 4AAH, 4COX, 4TS1
13GS, 1A07, 1A1B, 1A1E, 1A4K, 1A8T, 1AFQ, 1AKE, 1AVD, 1B59, 1B6J, 1B6K, 1B6L, 1B6M, 1BKM, 1BMQ, 1C2T, 1C3I, 1C5C, 1C5P, 1C5X, 1CBS, 1CDE, 1CDG, 1CET, 1COY, 1CQP, 1CTT, 1D0L, 1DIB, 1DY9, 1EVE, 1F0R, 1FBL, 1GKC, 1GPK, 1GSP, 1HBV, 1I7Z, 1IA1, 1IBG, 1ICN, 1IG3, 1IGJ, 1IVC, 1J3J, 1JJE, 1K7E, 1K7F, 1KEL, 1KZK, 1LMO, 1LPM, 1LYL, 1M48, 1MEH, 1MQ5, 1MRG, 1MRK, 1MTW, 1N46, 1NHU, 1NHV, 1ODW, 1OPK, 1PGP, 1Q4G, 1QH7, 1R1H, 1R55, 1RNT, 1S3V, 1SG0, 1SJ0, 1SLN, 1SNC, 1SQN, 1T40, 1T46, 1T9B, 1THL, 1THY, 1TLP, 1TPP, 1TZ8, 1U1C, 1V48, 1V4S, 1VCJ, 1XOZ, 1Y6B, 1YGC, 1Z95, 25C8, 2ADA, 2BM2, 2BSM, 2TPI, 3TPI, 4HMG, 4TMN, 5TIM, 5TMN, 6TMN
1AJ7, 1ATL, 1ETA, 1R09, 1VGC, 1VRH, 2R04, 2R07