Skip to content

@Merck Merck Sharp & Dohme Corp. a subsidiary of Merck & Co., Inc.

Change the repository type filter

All

    Repositories list

    78 repositories

    • Sapiens

      Public
      Sapiens is a human antibody language model based on BERT.
      embeddingsantibodylanguage-modelbertsapiens
      Jupyter Notebook
      •
      MIT License
      •17•54•1•0•Updated May 11, 2025May 11, 2025

    • gsDesign2

      Public
      Group Sequential Design Under Non-Proportional Hazards
      R
      •
      GNU General Public License v3.0
      •8•25•10•1•Updated May 9, 2025May 9, 2025

    • simtrial

      Public
      Clinical trial simulation for time-to-event endpoints
      R
      •
      GNU General Public License v3.0
      •8•21•6•3•Updated May 9, 2025May 9, 2025

    • BioPhi

      Public
      BioPhi is an open-source antibody design platform. It features methods for automated antibody humanization (Sapiens), humanness evaluation (OASis) and an interface for computer-assisted antibody sequence design.
      antibodyoasishumanizationsapienshumanness
      Python
      •
      MIT License
      •47•179•30•0•Updated May 9, 2025May 9, 2025

    • metalite.sl

      Public
      An R package designed for the analysis & reporting of subject baseline characteristics in clinical trials.
      R
      •
      GNU General Public License v3.0
      •1•0•3•1•Updated May 8, 2025May 8, 2025

    • r2rtf

      Public
      Easily Create Production-Ready Rich Text Format (RTF) Table and Figure
      R
      •
      GNU General Public License v3.0
      •22•79•2•0•Updated May 4, 2025May 4, 2025

    • gMCPLite

      Public
      Lightweight graph-based multiple comparison procedures
      R
      •
      GNU General Public License v3.0
      •3•13•0•0•Updated Apr 28, 2025Apr 28, 2025

    • forestly

      Public
      Interactive forest plot for adverse events analysis
      R
      •
      GNU General Public License v3.0
      •3•15•3•1•Updated Apr 18, 2025Apr 18, 2025

    • metalite.ae

      Public
      An R package for standard adverse events analysis
      metadataclinical-trialscdiscr-package
      R
      •
      GNU General Public License v3.0
      •4•20•3•0•Updated Mar 28, 2025Mar 28, 2025

    • wpgsd

      Public
      Weighted parametric group sequential design
      R
      •
      GNU General Public License v3.0
      •2•2•2•0•Updated Mar 27, 2025Mar 27, 2025

    • matcher-mmpdb

      Public
      Python
      •
      MIT License
      •2•7•0•0•Updated Mar 27, 2025Mar 27, 2025

    • ChemicalSpaceGeneration

      Public
      Jupyter Notebook
      •
      Other
      •2•0•0•0•Updated Feb 28, 2025Feb 28, 2025

    • psm3mkv

      Public
      psm3mkv: A package to evaluate the fit and efficiency of three state oncology cost-effectiveness model structures
      R
      •
      GNU General Public License v3.0
      •1•10•2•0•Updated Dec 18, 2024Dec 18, 2024

    • bgc-pipeline

      Public
      Jupyter Notebook
      •
      MIT License
      •1•11•2•0•Updated Dec 10, 2024Dec 10, 2024

    • CEEDesigns.jl

      Public
      A decision-making framework for the cost-efficient design of experiments, balancing the value of acquired experimental evidence and incurred costs.
      decision-makingjulia-languageexperimental-design
      Julia
      •
      Other
      •1•7•0•0•Updated Nov 22, 2024Nov 22, 2024

    • pkglite

      Public
      Compact Package Representations
      packageclinical-trialspackaging-toolectdpharmaverser
      R
      •
      GNU General Public License v3.0
      •4•29•5•0•Updated Nov 9, 2024Nov 9, 2024

    • metalite

      Public
      An R package to create metadata structure for ADaM data analysis and reporting
      metadataclinical-trialsr-packagecdisc
      R
      •
      GNU General Public License v3.0
      •6•16•2•0•Updated Aug 22, 2024Aug 22, 2024

    • AnNoBrainer

      Public archive
      0•0•0•0•Updated Aug 7, 2024Aug 7, 2024

    • puqsar

      Public
      Prediction Uncertainty for QSAR
      Python
      •
      GNU General Public License v3.0
      •1•0•0•0•Updated Jul 13, 2024Jul 13, 2024

    • MolPROP

      Public
      fuses molecular language and graph representation for property prediction
      Python
      •3•16•0•0•Updated Jun 1, 2024Jun 1, 2024

    • boxly

      Public
      Interactive box plot for clinical trial analysis
      R
      •
      GNU General Public License v3.0
      •1•12•5•0•Updated May 17, 2024May 17, 2024

    • ProbeDesign

      Public
      HTML
      •1•1•0•0•Updated May 9, 2024May 9, 2024

    • mRNAid

      Public
      Jupyter Notebook
      •
      Other
      •12•14•9•0•Updated May 6, 2024May 6, 2024

    • .github

      Public
      0•0•0•0•Updated May 1, 2024May 1, 2024

    • Line-of-Therapy-Algorithm

      Public
      This is the Line of Therapy Algorithm, as described in the paper "Temporal phenotyping by mining healthcare data to derive lines of therapy for cancer" pending submission in the Journal of Biomedical Informatics.
      Python
      •
      GNU General Public License v3.0
      •17•30•2•1•Updated Apr 29, 2024Apr 29, 2024

    • AbLEF

      Public
      Antibody Langauge Ensemble Fusion - fuses antibody structural ensemble and language representation for property prediction
      Python
      •3•11•0•0•Updated Apr 23, 2024Apr 23, 2024

    • ReactiveDynamics.jl

      Public
      A Julia package that implements a category of reaction (transportation) network-type dynamical systems.
      optimizationdecision-makingjulia-languagereaction-networkstrategic-planningdifferential-equationsscientific-machine-learning
      Julia
      •
      Other
      •3•17•1•1•Updated Apr 23, 2024Apr 23, 2024

    • rdf2x

      Public
      RDF2X converts big RDF datasets to the relational database model, CSV, JSON and ElasticSearch.
      jsonsqllinked-datasparqlrdfconversionpostgresqlspark
      Java
      •
      Apache License 2.0
      •11•48•3•4•Updated Apr 15, 2024Apr 15, 2024

    • AbPROP

      Public
      Python
      •
      Apache License 2.0
      •1•6•0•0•Updated Mar 23, 2024Mar 23, 2024

    • AlgebraicAgents.jl

      Public
      A lightweight framework to enable hierarchical, heterogeneous dynamical systems co-integration. Batteries included!
      juliajulia-languagedynamical-systemsdifferential-equationsstochastic-processes
      Julia
      •
      Other
      •3•21•0•1•Updated Mar 18, 2024Mar 18, 2024