Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

bad results observed in training and evaluating DeepHiC at 5kb #9

Open
zhyanlin opened this issue Jan 4, 2023 · 1 comment
Open

Comments

@zhyanlin
Copy link

zhyanlin commented Jan 4, 2023

Hello,

I'm trying to train a DeepHiC model at 5kb resolution.

I used 1/16 downsampled GM12878 data as input and trained DeepHiC with default parameters. During training, I observed both loss_D and loss_G were not improved for a very long time.
[400/1000] Loss_D: 0.0000 Loss_G: 0.0013 D(x): 1.0000 D(G(z)): 0.0000
I trained it for a very long time. It reached 0.0000, and 0.0013 around 100 epochs. The Best SSIM is ~0.901.
Here is an example of the prediction of a 180x180 window. Could you suggest how to update the parameters to train a better model or share a trained model at 5kb if you have one? It would be helpful if you could also share training plots such as loss v.s. epoch so I can compare it with mine.

image

Thanks!

@YuantingMaSC
Copy link

It looks like your reproduction of the paper went much smoother than mine, I'd like to ask you how you drew your SSMI and the example HiC plots, I didn't find the corresponding scripts in the project

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

2 participants