You signed in with another tab or window. Reload to refresh your session.You signed out in another tab or window. Reload to refresh your session.You switched accounts on another tab or window. Reload to refresh your session.Dismiss alert
As described in #145, adding more typing tools could allow us (among other things) to set up a result combination algorithm. If you compare it to other, HLAscan do not offer the best results (according to this and this benchmark for exemple) but is easy to setup and dataset used should be updatable (from IMGT/HLA EMBL flat file and some awk magic powder).
Algorithm/tool short description
All HLA typing algorithms can be divided into two broad categories: methods that assemble small reads de novo into longer contigs, and methods that directly match reads to HLA reference sequences. HLAscan belongs to the second group. At least 4 fields resolution is expected for class I and II loci.
Similar issue (saw also the discussion on Slack): Licencing and only binaries available 👎🏻 Epitopeprediction had similar issues, where eventually some open source method provided better rersults than the proprietary closed source thing and we "kind of dropped" it there (mhcpan / netmhcpan).
Description of feature
Hello,
As described in #145, adding more typing tools could allow us (among other things) to set up a result combination algorithm. If you compare it to other,
HLAscan
do not offer the best results (according to this and this benchmark for exemple) but is easy to setup and dataset used should be updatable (from IMGT/HLA EMBL flat file and some awk magic powder).Algorithm/tool short description
All HLA typing algorithms can be divided into two broad categories: methods that assemble small reads de novo into longer contigs, and methods that directly match reads to HLA reference sequences.
HLAscan
belongs to the second group. At least 4 fields resolution is expected for class I and II loci.Original paper
https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-017-1671-3
Source code/binary
Source code is not available, only binaries : https://github.com/SyntekabioTools/HLAscan
Licence
HLAscan software is freely available for academic purposes and a license is required for commercial download and installation
The text was updated successfully, but these errors were encountered: