---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
nocite: |
  @grandeGenomewideDiscoverySomatic2019, 
---
[[_TOC_]]


## Relevance tier by entity

[[include:tables/table1_TCL1A.md]]


## Mutation incidence in large patient cohorts (GAMBL reanalysis)

### DLBCL
[[include:tables/DLBCL_TCL1A.md]]

### BL
[[include:tables/BL_TCL1A.md]]

## Mutation pattern and selective pressure estimates

[[include:tables/dnds_TCL1A.md]]

## aSHM regions

|chr_name|hg19_start|hg19_end|region                                                                                    |regulatory_comment|
|:--------:|:----------:|:--------:|:------------------------------------------------------------------------------------------:|:------------------:|
|chr14   |96179535  |96180366|[TSS](https://genome.ucsc.edu/s/rdmorin/GAMBL%20hg19?position=chr14%3A96179535%2D96180366)|active_promoter   |



[[include:tables/browser_TCL1A.md]]

## Expression
![](images/gene_expression/TCL1A_by_pathology.svg)

[[include:tables/mermaid_TCL1A.md]]

## References

<!-- ORIGIN: grandeGenomewideDiscoverySomatic2019 -->
<!-- BL: grandeGenomewideDiscoverySomatic2019 -->