Mixcr built in reference

[pbpayal]

What's the builtin reference for Mixcr ? Is it IMGT?

The link - "gene library" mentioned here isn't working. So wanted to check.

The built-in reference gene library of V-, D-, J- and C- segments is thoroughly compiled for every available species using the data specifically obtained from multiple dedicated sequencing runs as well as from hundreds of other experiments. At the same time MiXCR supports using of external libraries or even to assemble a custom library from scratch.

[mizraelson]

Hi, MiXCR uses its own reference by default, not IMGT. We manually create and keep it up to date.

[pbpayal]

What are your sources for creating the reference?

[mizraelson]

It is a genome-based reference based on the latest assembly.

[pbpayal]

Latest assembly from where?
I have an upcoming presentation. I need this information because I have been asked this question before!

[mizraelson]

For human: https://www.ncbi.nlm.nih.gov/datasets/genome/GCF_009914755.1/
For mouse: https://www.ncbi.nlm.nih.gov/datasets/genome/GCF_000001635.26/

[pbpayal]

Thank you..thats helpful.