diff --git a/DESCRIPTION b/DESCRIPTION index 05c9d34b..0b3b86c9 100644 --- a/DESCRIPTION +++ b/DESCRIPTION @@ -1,7 +1,7 @@ Package: mvMAPIT Type: Package Title: Implements the Multivariate MArginal ePIstasis Test (mvMAPIT) from Crawford et al. 2017 -Version: 0.1.2 +Version: 0.1.1 Author: lcrawlab Maintainer: Lorin Crawford Description: Epistasis, commonly defined as the interaction between multiple genes, is an important genetic component underlying phenotypic variation. Many statistical methods have been developed to model and identify epistatic interactions between genetic variants. However, because of the large combinatorial search space of interactions, most epistasis mapping methods face enormous computational challenges and often suffer from low statistical power. In Crawford et al. (2017), we present a novel, alternative strategy for mapping epistasis: the MArginal ePIstasis Test (MAPIT). Our method examines one variant at a time, and estimates and tests its "marginal epistatic effects" --- the combined pairwise interaction effects between a given variant and all other variants. By avoiding explicitly searching for interactions, our method avoids the large combinatorial search space and improves power. Our method is novel and relies on a recently developed variance component estimation method for efficient and robust parameter inference and p-value computation. diff --git a/configure b/configure index 33f94c06..ecf14ee2 100755 --- a/configure +++ b/configure @@ -1,6 +1,6 @@ #! /bin/sh # Guess values for system-dependent variables and create Makefiles. -# Generated by GNU Autoconf 2.71 for mvMAPIT 0.1.2. +# Generated by GNU Autoconf 2.71 for mvMAPIT 0.1.1. # # # Copyright (C) 1992-1996, 1998-2017, 2020-2021 Free Software Foundation, @@ -607,8 +607,8 @@ MAKEFLAGS= # Identity of this package. PACKAGE_NAME='mvMAPIT' PACKAGE_TARNAME='mvmapit' -PACKAGE_VERSION='0.1.2' -PACKAGE_STRING='mvMAPIT 0.1.2' +PACKAGE_VERSION='0.1.1' +PACKAGE_STRING='mvMAPIT 0.1.1' PACKAGE_BUGREPORT='' PACKAGE_URL='' @@ -1270,7 +1270,7 @@ if test "$ac_init_help" = "long"; then # Omit some internal or obsolete options to make the list less imposing. # This message is too long to be a string in the A/UX 3.1 sh. cat <<_ACEOF -\`configure' configures mvMAPIT 0.1.2 to adapt to many kinds of systems. +\`configure' configures mvMAPIT 0.1.1 to adapt to many kinds of systems. Usage: $0 [OPTION]... [VAR=VALUE]... @@ -1332,7 +1332,7 @@ fi if test -n "$ac_init_help"; then case $ac_init_help in - short | recursive ) echo "Configuration of mvMAPIT 0.1.2:";; + short | recursive ) echo "Configuration of mvMAPIT 0.1.1:";; esac cat <<\_ACEOF @@ -1415,7 +1415,7 @@ fi test -n "$ac_init_help" && exit $ac_status if $ac_init_version; then cat <<\_ACEOF -mvMAPIT configure 0.1.2 +mvMAPIT configure 0.1.1 generated by GNU Autoconf 2.71 Copyright (C) 2021 Free Software Foundation, Inc. @@ -1648,7 +1648,7 @@ cat >config.log <<_ACEOF This file contains any messages produced by compilers while running configure, to aid debugging if configure makes a mistake. -It was created by mvMAPIT $as_me 0.1.2, which was +It was created by mvMAPIT $as_me 0.1.1, which was generated by GNU Autoconf 2.71. Invocation command line was $ $0$ac_configure_args_raw @@ -4714,7 +4714,7 @@ cat >>$CONFIG_STATUS <<\_ACEOF || ac_write_fail=1 # report actual input values of CONFIG_FILES etc. instead of their # values after options handling. ac_log=" -This file was extended by mvMAPIT $as_me 0.1.2, which was +This file was extended by mvMAPIT $as_me 0.1.1, which was generated by GNU Autoconf 2.71. Invocation command line was CONFIG_FILES = $CONFIG_FILES @@ -4769,7 +4769,7 @@ ac_cs_config_escaped=`printf "%s\n" "$ac_cs_config" | sed "s/^ //; s/'/'\\\\\\\\ cat >>$CONFIG_STATUS <<_ACEOF || ac_write_fail=1 ac_cs_config='$ac_cs_config_escaped' ac_cs_version="\\ -mvMAPIT config.status 0.1.2 +mvMAPIT config.status 0.1.1 configured by $0, generated by GNU Autoconf 2.71, with options \\"\$ac_cs_config\\" diff --git a/configure.ac b/configure.ac index 82075ce9..d0d1a79e 100644 --- a/configure.ac +++ b/configure.ac @@ -1,4 +1,4 @@ -AC_INIT([mvMAPIT],[0.1.2]) +AC_INIT([mvMAPIT],[0.1.1]) # Find the compiler and compiler flags used by R. : ${R_HOME=`R RHOME`}