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<html>
<head>
<meta charset="utf-8" />
<meta name="viewport" content="width=device-width, initial-scale=1.0" />
<link
rel="stylesheet"
type="text/css"
href="semantic/dist/semantic.min.css"
/>
<title>ReSeq: Repurposing HiSeq DNA Sequencers</title>
<meta
name="description"
content="We are writing free and open source software to drive HiSeq2000/2500 DNA sequencers. We want to avoid the waste of this decomissioned equipment by re-purposing it for high resolution fluorescence microscopy and more. Crowd funding early 2019."
/>
<!-- Google / Search Engine Tags -->
<meta itemprop="name" content="ReSeq" />
<meta
itemprop="description"
content="We are writing free and open source software to drive HiSeq2000/2500 DNA sequencers. We want to avoid the waste of this decomissioned equipment by re-purposing it for high resolution fluorescence microscopy and more. Crowd funding early 2019."
/>
<meta
itemprop="image"
content="https://reseq.netlify.com/291px-DaphniaCompositeScaleCrop.jpg"
/>
<!-- Facebook Meta Tags -->
<meta property="og:type" content="website" />
<meta property="og:title" content="ReSeq" />
<meta
property="og:description"
content="We are writing free and open source software to drive HiSeq2000/2500 DNA sequencers. We want to avoid the waste of this decomissioned equipment by re-purposing it for high resolution fluorescence microscopy and more. Crowd funding early 2019."
/>
<meta
property="og:image"
content="https://reseq.netlify.com/291px-DaphniaCompositeScaleCrop.jpg"
/>
<meta property="og:image:width" content="291" />
<meta property="og:image:height" content="500" />
<!-- Twitter Meta Tags -->
<meta name="twitter:card" content="summary_large_image" />
<meta name="twitter:title" content="ReSeq" />
<meta
name="twitter:description"
content="We are writing free and open source software to drive HiSeq2000/2500 DNA sequencers. We want to avoid the waste of this decomissioned equipment by re-purposing it for high resolution fluorescence microscopy and more. Crowd funding early 2019."
/>
<meta
name="twitter:image"
content="https://reseq.netlify.com/291px-DaphniaCompositeScaleCrop.jpg"
/>
<style>
#email-signup-box {
display: flex;
margin-left: 5px;
padding-left: 10px;
margin-bottom: 100px;
}
#hiseq-image-box {
width: 100%;
display: flex;
justify-content: center;
}
@media (max-width: 1200px) {
#email-signup-box {
flex-wrap: wrap-reverse;
}
#email-signup-box > div {
margin-top: 40px;
}
}
@media (max-width: 514px) {
#hiseq-image-box > div > img {
width: 300px;
}
}
</style>
</head>
<body>
<div class="ui container vertical segment" style="padding-top:30px">
<h1 class="ui header">ReSeq: Repurposing HiSeq DNA Sequencers</h1>
</div>
<div style="margin-top:20px" class="ui container">
<div style="display:flex; flex-wrap:wrap;">
<div style="padding:10px; margin-bottom:40px;">
<a
href="http://www.gaudi.ch/GaudiLabs/wp-content/uploads/DaphniaCompositeScaleCrop.tif"
class="ui image"
data-tooltip="Download a high resolution version (167 Mb)"
data-position="top left"
data-inverted=""
>
<img
style="width:291px"
src="291px-DaphniaCompositeScaleCrop.jpg"
/>
</a>
</div>
<div
style="padding:10px; width:800px; margin-bottom:40px; font-size:15pt;"
>
<p>
The Illumina HiSeq 2000 and 2500 are advanced DNA sequencers
that have been replaced by a new generation. Institutes and
companies around the world are getting rid of them, they are now
available for a fraction of the original cost and can even be
obtained for free.
</p>
<p>
Urs Gaudenz managed to get a hold of a machine and document large
parts of the hardware and the internal communication protocol in
detail
<a
href="https://www.hackteria.org/wiki/HiSeq2000_-_Next_Level_Hacking"
>
on the Hackteria Wiki.
</a>
</p>
<p>
The image you see is a high resolution scan of a water-flea made
using an early prototype of the control software we are developing
(<a
href="http://www.gaudi.ch/GaudiLabs/wp-content/uploads/DaphniaCompositeScaleCrop.tif"
>full resolution</a
>). The combination of bright light and fluorescent scanning shows
the micro-plastic ingested by the perished animal and indicates the
disturbing consequences of disposed plastics decomposing in our
natural environments.
</p>
<p>
The HiSeqs are high resolution microscopic instruments with a large
scan area, a precision movable stage, multi-channel fluorescence
capabilities as well as microfluidics flow cells. They have
countless other applications for researchers and citizen scientists
if there were usable software to drive them.
</p>
</div>
<div id="email-signup-box">
<div style="min-width:350px;">
<ul class="ui list" style="font-size:14pt">
<li>
<a
href="https://wemakeit.com/projects/reseq-reuse-dna-sequencers?locale=en"
>
SUCCESSFUL CROWD FUNDING CAMPAIGN ON WEMAKEIT.COM
</a>
</li>
<li>
<a
href="https://github.com/kasbah/reseq-website/blob/master/balance.csv"
>
How is the money being spent?
</a>
</li>
<li>
<a href="https://reseq.hackteria.org/faq">
Frequently asked questions
</a>
</li>
<li>
<a href="https://forum.hackteria.org/c/reseq">
Join our forum
</a>
</li>
<li>
<a
href="https://www.hackteria.org/wiki/HiSeq2000_-_Next_Level_Hacking"
>
Read the documentation on our wiki
</a>
</li>
<li>
<a
href="https://hackaday.com/2019/01/15/deep-discounts-yield-deep-reverse-engineering-of-biotech-hardware/"
>
Summary article from Hackaday
</a>
</li>
</ul>
</div>
<div id="hiseq-image-box">
<div><img src="400px-HiSeq.jpg" /></div>
</div>
<div>
<p style="font-size:12pt">
JOIN OUR EMAIL LIST TO BE NOTIFIED OF UPDATES
</p>
<form
class="ui form"
name="contact"
method="POST"
data-netlify="true"
style="padding:15px"
>
<div class="field">
<label>Your Email</label>
<div class="ui action input">
<input type="email" name="email" />
<button class="ui button" type="submit">Submit</button>
</div>
</div>
</form>
</div>
</div>
</div>
</div>
</body>
</html>