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README.md
@@ -214,6 +214,13 @@ The `--is_prokaryote_list` flag has been removed along with the `is_prokaryote`
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argument in `run_alphafold.predict_structure()`, eukaryotes and prokaryotes are
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now paired in the same way.
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+To use the deprecated v2.1.0 AlphaFold-Multimer model weights:
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+
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+1. Change `SOURCE_URL` in `scripts/download_alphafold_params.sh` to
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+`https://storage.googleapis.com/alphafold/alphafold_params_2022-01-19.tar`,
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+and download the old parameters.
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+2. Remove the `_v2` in the multimer `MODEL_PRESETS` in `config.py`.
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## Running AlphaFold
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**The simplest way to run AlphaFold is using the provided Docker script.** This
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