diff --git a/azure-pipelines.yml b/azure-pipelines.yml
index 7b4a7abf0..981697ede 100644
--- a/azure-pipelines.yml
+++ b/azure-pipelines.yml
@@ -42,7 +42,7 @@ jobs:
   variables:
     HDF5_VERSION: 1.12.1
     HDF5_DIR: $(HDF5_CACHE_DIR)/$(HDF5_VERSION)
-    HDF5_VSVERSION: "15-64"
+    HDF5_VSVERSION: "16-64"
     CIBW_BUILD: cp3{7,8,9,10}-win_amd64
   steps:
     - template: ci/azure-pipelines-wheels.yml
@@ -179,7 +179,7 @@ jobs:
         TOXENV: py37-test-deps,py37-test-deps-pre
         HDF5_VERSION: 1.8.17
         HDF5_DIR: $(HDF5_CACHE_DIR)/$(HDF5_VERSION)
-        HDF5_VSVERSION: "15-64"
+        HDF5_VSVERSION: "16-64"
         H5PY_ENFORCE_COVERAGE: yes
     # 64 bit - HDF5 1.10
       py38-hdf5110:
@@ -187,14 +187,14 @@ jobs:
         TOXENV: py38-test-deps,py38-test-mindeps,py38-test-deps-pre
         HDF5_VERSION: 1.10.6
         HDF5_DIR: $(HDF5_CACHE_DIR)/$(HDF5_VERSION)
-        HDF5_VSVERSION: "15-64"
+        HDF5_VSVERSION: "16-64"
         H5PY_ENFORCE_COVERAGE: yes
       py39-hdf5110:
         python.version: '3.9'
         TOXENV: py39-test-deps,py39-test-mindeps,py39-test-deps-pre
         HDF5_VERSION: 1.10.6
         HDF5_DIR: $(HDF5_CACHE_DIR)/$(HDF5_VERSION)
-        HDF5_VSVERSION: "15-64"
+        HDF5_VSVERSION: "16-64"
         H5PY_ENFORCE_COVERAGE: yes
     # 64 bit - HDF5 1.12
     # Fewer combinations here; test_windows_wheels also tests HDF5 1.12
@@ -203,7 +203,7 @@ jobs:
         TOXENV: py38-test-deps
         HDF5_VERSION: 1.12.0
         HDF5_DIR: $(HDF5_CACHE_DIR)/$(HDF5_VERSION)
-        HDF5_VSVERSION: "15-64"
+        HDF5_VSVERSION: "16-64"
         H5PY_ENFORCE_COVERAGE: yes
     maxParallel: 4
 
diff --git a/ci/get_hdf5_win.py b/ci/get_hdf5_win.py
index 0db6c6ce2..7242959b2 100644
--- a/ci/get_hdf5_win.py
+++ b/ci/get_hdf5_win.py
@@ -48,7 +48,7 @@
     "10-64": "Visual Studio 10 2010 Win64",
     "14-64": "Visual Studio 14 2015 Win64",
     "15-64": "Visual Studio 15 2017 Win64",
-    "16-64": "Visual Studio 16 2019 Win64",
+    "16-64": "Visual Studio 16 2019",
 }