README.md

R code to accompany Surrogacy Validation with Longitudinal Outcomes for a Gene Therapy manuscript

Information here

Resources

• Ask a question/ Open an issue: coming soon (GitHub issues for bug reports, feature requests)

Development Version

The most recent development release can be installed from Github via devtools.

install.packages("devtools")

#devtools::install_github("emilykroberts/Surrogacy-Validation-Longitudinal-Outcomes")

Help/Getting started

Once installed, load the package

#library("Surrogacy-Validation-Longitudinal-Outcomes")
library("surrogacy")

Details

The R package requires R. Pre-build binaries for the current official release of the package are available from CRAN (Comprehensive R Archive Network), but if the user desires to compile the package for himself, then the typical R compiler tools will have to be installed. Instructions can be found on the R Projects website at https://www.r-project.org/nosvn/pandoc/devtools.html.

The latest development version of the package can be found on Github.

See the README on the Github repository page for additional details about package installation.

Core functionality

Assess surrogacy value of a surrogate for longitudinal true outcomes when surrogate and true outcomes are normally distributed. Currently uses random intercept models.

Contributing

If you are interested in contributing to the development please open an issue to request.

References and other literature

Paper available