Installing ipyrad on Mac M1/M2 (osx-arm64)

[isaacovercast]

Bioconda currently does not support osx-arm64 builds, but looks like it is scheduled to some time later in 2023.

I am messing around with different ways to try to get it installed anyway, but haven't had luck so far. Will update the issue if I make any progress.

[isaacovercast]

Related: conda/conda#11216

[isaacovercast]

I figured out how to get ipyrad installed on a Mac M1/M2 by switching the Terminal to x86 mode. It's slow and hackish, but it works:

https://ipyrad.readthedocs.io/en/master/3-installation.html#installing-ipyrad-on-mac-m1-m2

[isaacovercast]

ipyrad now builds an osx-arm64 version, but some dependencies remain missing.

Per this comment in the bioconda github announcements issue, osx-arm64 builds are now available (you currently have to opt in). I updated our bioconda recipe and it builds fine. There are still several dependencies we pull from bioconda that do not have the arm64 build enabled yet:

• cutadapt
• dnaio
• muscle

Current bioconda recipe PR (active 8/17/24).

[isaacovercast]

cutadapt/dnaio/muscle are now all built for osx-arm64. ipyrad is still blocked from running on this architecture because the bioconda recipe infrastructure and github repo are tailored around muscle v5 . We can fix this in one of two ways:

• Update the muscle bioconda recipe to build v3 for osx-arm64 (w/ a subrecipe)
• Fix ipyrad to support muscle v5 (Support for muscle v5 #572)

Both of these are painful.