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DESCRIPTION
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Package: BisqueRNA
Title: Decomposition of Bulk Expression with Single-Cell Sequencing
Version: 1.0.5
Authors@R: c(
person(given = 'Brandon', family = 'Jew', email = '[email protected]', role = c('aut', 'cre')),
person(given = 'Marcus', family = 'Alvarez', role = 'aut')
)
Description: Provides tools to accurately estimate cell type abundances
from heterogeneous bulk expression. A reference-based method utilizes
single-cell information to generate a signature matrix and transformation
of bulk expression for accurate regression based estimates. A marker-based
method utilizes known cell-specific marker genes to measure relative
abundances across samples.
For more details, see Jew and Alvarez et al (2019) <doi:10.1101/669911>.
Depends: R (>= 3.5.0)
License: GPL-3
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.0.2
biocViews:
Imports:
Biobase,
limSolve,
methods,
stats
Suggests:
Seurat,
plyr,
knitr,
rmarkdown,
testthat
URL: https://www.biorxiv.org/content/10.1101/669911v1
BugReports: https://github.com/cozygene/bisque/issues
VignetteBuilder: knitr