qnrom in config.yaml for different cells

[JasonLinjc]

Dear Team,

I wanted to express my deepest appreciation for creating such remarkable tools for predicting promoter-enhancer interactions. They have proven to be tremendously helpful!

I have a quick question about the use of the pipeline for different cell lines. Should I modify the "qnorm" parameter in the config.yaml file, specifically changing it from "reference/EnhancersQNormRef.K562.txt", when running the pipeline for other cell lines?

Thank you for your assistance!

Best,
Jiecong

[engreitz]

Hi Jiecong, No, you should not modify the qnorm parameter. Use the provided file Best, Jesse

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On Sat, Aug 3, 2024 at 10:19 AM Jiecong Lin ***@***.***> wrote: Dear Team, I wanted to express my deepest appreciation for creating such remarkable tools for predicting promoter-enhancer interactions. They have proven to be tremendously helpful! I have a quick question about the use of the pipeline for different cell lines. Should I modify the *"qnorm"* parameter in the *config.yaml* file, specifically changing it from *"reference/EnhancersQNormRef.K562.txt"*, when running the pipeline for other cell lines? Thank you for your assistance! Best, Jiecong — Reply to this email directly, view it on GitHub <#231>, or unsubscribe <https://github.com/notifications/unsubscribe-auth/AA3LGECQNH54IKDSQBJVJULZPTYIXAVCNFSM6AAAAABL57ZDEWVHI2DSMVQWIX3LMV43ASLTON2WKOZSGQ2DMNBQGQ3TKNI> . You are receiving this because you are subscribed to this thread.Message ID: ***@***.***>

-- Jesse Engreitz, PhD Assistant Professor, Department of Genetics BASE Research Initiative, Betty Irene Moore Children’s Heart Center Stanford University School of Medicine www.engreitzlab.org +1 (206) 310-3935 Pronouns: He/him/his