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MultiPhentype Simulation with MinP #51

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jrahimik opened this issue Aug 1, 2018 · 6 comments
Open

MultiPhentype Simulation with MinP #51

jrahimik opened this issue Aug 1, 2018 · 6 comments

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@jrahimik
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jrahimik commented Aug 1, 2018

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@jrahimik jrahimik self-assigned this Aug 1, 2018
@jrahimik
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jrahimik commented Aug 21, 2018 •
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The pvalues will be update

@kayhan-batmanghelich
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@jrahimik if this is the p-val distribution of minP then there is no inflation. Something is missing here.

@jrahimik
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jrahimik commented Aug 21, 2018 •
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image

image

From this two graph we can see that the p values are getting inflated as the number of phenotypes increasing. The next step is to try different correcting methods and see the power on those correction criteria.

@kayhan-batmanghelich
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@jrahimik and explanation?

@jrahimik
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Explanation was added.

@kayhan-batmanghelich
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@jrahimik can you generate ROC for this?

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@kayhan-batmanghelich @jrahimik