Splicing Analysis based on STAR quantifications

[andrebolerbarros]

Hello @alexdobin,

I have a dataset in which we are looking at canonical events vs noncanonical events (intro retention, alternative splicing, etc.). We were considering using STAR in a way were we can obtain counts only for canonical events and noncanonical events, to compare the quantifications afterwards.

Do you think it is possible to use solely STAR to get these quantifications? If so, which would be the arguments one should change?

Best regards,
André

[wososa]

Hi Andre, You absolutely can. PSI-Sigma was developed based on only STAR quantifications! Best, Woody

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On Thu, Dec 19, 2024 at 10:11 AM André Barros ***@***.***> wrote: Hello @alexdobin <https://github.com/alexdobin>, I have a dataset in which we are looking at canonical events vs noncanonical events (intro retention, alternative splicing, etc.). We were considering using STAR in a way were we can obtain counts only for canonical events and noncanonical events, to compare the quantifications afterwards. Do you think it is possible to use solely STAR to get these quantifications? If so, which would be the arguments one should change? Best regards, André — Reply to this email directly, view it on GitHub <#2259>, or unsubscribe <https://github.com/notifications/unsubscribe-auth/ABWLHWISZ7436BK7RGMYKP32GLO2LAVCNFSM6AAAAABT5GOST2VHI2DSMVQWIX3LMV43ASLTON2WKOZSG42TANRUGIZDSMQ> . You are receiving this because you are subscribed to this thread.Message ID: ***@***.***>