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Cluster parameter, neighbors defintion & other issues for method implementation #198

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Jieran-S opened this issue Feb 12, 2024 · 1 comment
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@Jieran-S
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Some issues I found in the current implementation:

  1. Some implementation omits customized preprocess steps: DeepST. did @shdam find anything from the methods you worked on?

  2. Some implementations don't use existing neighbor graphs: scanpy, seurat, SOTIP all use standard scanpy or seurat neighbor construction methods. They can use existing neighbor graphs

  3. Clustering using resolution instead of clusters_number: SOTIP, SpaceFlow, STAGATE, SCAN-IT. Can implement grid-search to convert resolution into cluster_number definition.

Would these issues make sense? if so I will update them @niklasmueboe @naveedishaque

@Jieran-S Jieran-S self-assigned this Feb 12, 2024
@shdam
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shdam commented Feb 13, 2024

Regarding 3. Seurat and stardust have the same issue. I implemented a resolution tuning function for those.

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