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Multi-ancestry PRS practical

Learning objectives

  • Understand the two datasets
  • Look for differences in the effect sizes across populations
  • Examine why differences in effect sizes might arise
  • Investigate the performance of the PRS across populations

Instructions

  • Use the practical.rmd file to complete the practical.
  • You will need to install ggplot2 and dplyr.
  • The script includes steps to obtain the data directly from github.
  • The students are expected to
    • read the instructions
    • run the code and interpret the results
    • fill in sections where QUESTIONS are asked
    • add extra code blocks where TASKS are asked