Phenotype definitions

We are currently including the following set of phenotypes in this analysis round. To be included a cohort will need to provide at least one phenotype. The list is somewhat aspirational and if bandwidth limits the number of phenotypes that can be contributed, that is fine.

Anthropometric

• Body Mass Index - In kg/m2
• Height - Standing height in centimetres
• Waist circumference - Measured in cm
• Waist to hip ratio - Measured in cm/cm
• Heel bone mineral density
  • Measured in ??
  • Key previous GWASs - https://pubmed.ncbi.nlm.nih.gov/28869591/
• Forced vital capacity,fvc,cont,l,0,10,sex,ebi-a-GCST90029027
• Forced expiratory volume in 1 second,fev1,cont,l,0,10,sex,ukb-b-19657
• FEV1/FVC ratio,fev1fvc,cont,l,0,10,sex,ebi-a-GCST90029026

Cardiovascular

• Systolic blood pressure,sbp,cont,
• Diastolic blood pressure,dbp,cont,

Blood measures

• LDL cholesterol,ldl,cont,mmol/L,0,200,sex:cholesterol_med,ieu-b-110
• HDL cholesterol,hdl,cont,mmol/L,0,200,sex:cholesterol_med,ieu-b-109
• Triglicerides,trig,cont
• Leptin,leptin,cont
• Insulin,insulin,cont
• Adiponectin,adiponectin,cont
• Calcium,calcium,cont
• Vitamin D,vitd,cont

Immune markers

• CRP,crp,cont
• IL6,il6,cont

Sex hormones

• Estrogen,estrogen,cont
• Progesterone,progesterone,cont
• Testosterone,testosterone,cont

Neuropsychiatric

• Cognitive function,cognition,cont
• Depression scores,depression,cont